The aim of this case report is the evaluation of the follow-up and treatment process in a patient with the diagnosis of autism spectrum disorder (ASD). A patient with ASD had social regression, limited eye contact, abdominal pain, and constipation. Urine lead, mercury and aluminum levels were above the normal range. Intestinal flora analysis found severe dysbiosis and intestinal inflammation. A combined preparation (Chlorella vulgaris, Coriandrum sativum, and probiotics) and a sugar, casein, and lactose-free diet were continued for one year. After 1 year; mercury level was normal and lead level was decreased. Constipation and pain were also relieved.

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