Oral anticoagulant therapy should be monitored closely because of potential side effects. In this present study, we aimed to report a case of spontaneously occurred intramurral hematoma due to warfarin usage. Fifty-five years old female patient was admitted to emergency department due to abdominal pain, vomiting and skin ecchymosis. History of the patient revealed usage of Warfarin (5 mg/day) due to atrial fibrillation for one year. Abdominal tenderness and rebound was detected, especially in lower quadrant. INR level was too high to measure. Abdominal CT revealed occurrence of intramural hematoma. Vitamin K and fresh frozen plasma were applied intravenously. Patient was discharged after 6 days of hospitalization, uneventfully. There was no complication following three years.

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