ABSTRACT
Background:
In hematopoetic stem cell transplant (HSCT) recipients, moulds have emerged as a major cause of mortality and incidence of invasive aspergillosis has been shown to be increased. Rapid diagnostic procedures are needed in order to diagnose invasive fungal infections especially aspergillus infections.
METHODS:
In this retrospective study, in their neutropenic fever episodes the results of galactomannan tests (GM) (Platelia Aspergillus test, Bio-Rad, France) applied 37 stem cell transplant patients in Yeditepe University Hospital, were handled. Galactomannan results were evaluated by blood or sputum cultures and/or fungal PCR. The total number of tests applied to these samples were 69..
RESULTS:
Among four ex patients, everything was correlated in only one patient. From 66 PCR tests, 3 tests (4,5%); from 69 GM tests 6 tests (9%) were found as positive.
CONCLUSION:
The definition of invasive fungal disease and treatment and diagnosis guidelines are revised and the place of the galactomannan test and PCR is still being discussed; such studies should take place for also standardization and validation of these tests.
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