ABSTRACT
PURPOSE:
Lymphoma is the malignant neoplasm of the lymphoid system. CT and MRI appearances can be diverse, and almost all organ systems can be involved. The diagnosis of extranodal lymphoma is challenging, since almost all other pathologic conditions including neoplasms can mimic this disease. We aimed to illustrate CT and MRI findings of lymphoma in various extranodal sites.
MATERIAL AND METHOD:
CT and MRI examination findings were presented to illustrate the diversity of the radiological appearances and organs involved.
RESULTS:
Among all lymphoma subjects, extranodal disease accounts for 15% of patients. We aimed to demonstrate some special clues for each system to help the differential diagnosis of extranodal lymphoma. GIS: Intestinal mural thickening with adjacent lymph node enlargement without obstructive symptoms, and with possible additional aneurysmatic dilatation. Genitourinary: Patchy hypodense or hypointense areas through the parenchyma, bilaterally. Thoracic: uniformly but nonsegmental thickening of the vascular, and/or cardiac wall. Pulmonary parenchymal involvement may present with any configuration such as ground-glass appearance, infiltration, mass, nodule etc. Central nervous system: Atypically presented a nonmass-like lesion with minimal contrast enhancement. Bone, muscle and soft tissues: Homogenous mass lesion with minimal or relative large area of necrosis and permeative growth without obvious destruction.
CONCLUSION:
Lymphoma is a common malignancy, accurate diagnosis is crucial for the treatment strategy. This pictorial review will make radiologists familiar with the imaging findings of lymphomas affecting various extranodal sites.
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